Endocrine Abstracts

This retrospective cohort study examined Hospital Episode Statistics (HES) and Hospital Pharmacy Audit (HPA) data from 41 hospital trusts to understand how hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) is currently treated in England, and to understand the associated resource use. Hyponatraemia is the electrolyte disturbance that is most commonly encountered in clinical practice (affecting 10–30% of hospitalised patients), wit...

Objectives: International and national guidelines on the treatment of chronic non-hypovolaemic hypotonic hyponatraemia differ widely. Using methods embodied in the Cochrane Handbook, a systematic review and meta-analysis was conducted to investigate the efficacy and safety of interventions for this condition.Methods: Following registration of the review protocol with PROSPERO (CRD42015016670), systematic literature searches were conducted to identify ran...